CompletedNot Applicable

Long-term Effects of SCL-wearing on Corneal Neuromediators and Postoperative Rehabilitation After SMILE

China90 participantsStarted 2023-06-01

Plain-language summary

To investigate the effects of neuromediators in corneal stromal lenticules from patients with long-term soft contact lens (SCL) wear on corneal nerve regeneration and visual quality recovery following small incision lenticule extraction (SMILE).

Who can participate

Age range18 Years – 45 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age ≥ 18 years with stable refraction for at least two years; * corrected distance visual acuity of 20/20 or better; * no history of using rigid gas permeable lenses or orthokeratology (OK) lenses prior to examination Exclusion Criteria: \- a history of moderate to severe dry eye as well as any ocular or systemic disease that would contraindicate laser refractive surgery.

What they're measuring

Quality of Vision (QOV) scores

Timeframe: baseline, 1 month, 3months, 6months

contrast sensitivity function

Timeframe: baseline, 1moth, 3 moths, 6 months

Corneal subepithelial nerve fibers

Timeframe: baseline, 1moth, 3 moths, 6 months

Corneal stromal lenticule Neuromediators

Timeframe: baseline

OSDI Questionnaire

Timeframe: baseline, 1moth, 3 moths, 6 months

Trial details

NCT IDNCT07001306

Sponsoryuhao shao

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-06-30

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