CompletedNot Applicable

Dobutamine During Major Abdominal Surgery

Germany100 participantsStarted 2025-06-16

Plain-language summary

The PUSH-1 trial is a randomized, single-center pilot trial investigating whether dobutamine administration is feasible in patients having major abdominal surgery.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Consenting patients ≥18 years scheduled for elective major abdominal surgery under general anesthesia (expected surgery duration ≥ 120 minutes) * Planned continuous intraarterial blood pressure monitoring using an arterial catheter for clinical indications not related to the trial Exclusion Criteria: * Emergency surgery * Liver or kidney transplantation surgery * Status of post transplantation of kidney, liver, heart, or lung * Pregnancy * Heart rhythms other than sinus rhythm

What they're measuring

Feasibility of dobutamine administration

Timeframe: During surgery (incision-to-suture)

Trial details

NCT IDNCT07000994

SponsorUniversity of Hamburg-Eppendorf

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-01-28

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