Splinting vs Exercise in De Quervain's Tenosynovitis (NCT06995534) | Clinical Trial Compass
RecruitingNot Applicable
Splinting vs Exercise in De Quervain's Tenosynovitis
Turkey (Türkiye)40 participantsStarted 2025-05-29
Plain-language summary
De Quervain's disease is a painful tenosynovitis of the abductor pollicis longus and extensor pollicis brevis muscle tendons located in the first dorsal compartment. The primary treatment for De Quervain's disease is conservative; surgical intervention is rarely required. Currently, there is no standardized treatment protocol supported by strong, up-to-date evidence.
The aim of this study is to compare the effectiveness of a static hand-wrist resting splint and exercise therapy in the conservative treatment of De Quervain's tenosynovitis. Patients will be evaluated in terms of pain levels, functional/symptom status, hand-finger strength, pressure pain threshold (PPT), tendon cross-sectional area measured by ultrasound, and the presence of effusion findings (semiquantitative; 0-3), and patient satisfaction.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults aged between 18 and 65 years
Patients experiencing wrist pain and tenderness for less than 3 months and clinically diagnosed with acute or subacute De Quervain's tenosynovitis
Visual Analog Scale (VAS) pain score ≥ 3
Exclusion Criteria:
* History of trauma
Wrist fractures
Local infection
Presence of rheumatologic diseases (e.g., rheumatoid arthritis, psoriatic arthritis)
Presence of symptomatic hand osteoarthritis
Continuous use of nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids
Receipt of physical therapy for the hand or wrist within the past 3 months
Corticosteroid injection into the hand or wrist within the past 3 months
Diagnosed with significant neurological disorders (e.g., upper motor neuron disease)
Presence of uncontrolled systemic diseases (e.g., uncontrolled diabetes mellitus, congestive heart failure, chronic kidney disease, hepatic failure)
Major psychiatric disorders
Communication difficulties
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
VAS pain
Timeframe: baseline, week 2 and week 6
2
Patient Rated Wrist Evaluation( PRWE)
Timeframe: baseline, week 2 and week 6
3
The Disabilities of the Arm, Shoulder and Hand (DASH)
Timeframe: baseline, week 2 and week 6
Trial details
NCT IDNCT06995534
SponsorKonya Beyhekim Training and Research Hospital