Dexmedetomidine as an Adjuvant to Bupivacaine in Scalp Block Versus Bupivacaine Alone for Postope… (NCT06993922) | Clinical Trial Compass
RecruitingNot Applicable
Dexmedetomidine as an Adjuvant to Bupivacaine in Scalp Block Versus Bupivacaine Alone for Postoperative Pain Management in Patients Undergoing Craniotomy
Egypt50 participantsStarted 2025-05-29
Plain-language summary
This study aims to compare dexmedetomidine as an adjuvant to bupivacaine in scalp block versus bupivacaine alone for postoperative pain management in patients undergoing craniotomy.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age from 18 to 65 years.
* Both sexes.
* American Society of Anesthesiologists (ASA) physical status I or II.
* Undergoing supratentorial elective planned craniotomies.
Exclusion Criteria:
* Patients refusal.
* History of known allergy to the used local anesthetic or dexmedetomidine.
* Bleeding disorders.
* Evidence of local infection at the site of injection.
* Emergency craniotomy.
* Psychotic disorder.
* Patients who will not be extubated in the operating room after surgery.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is comparing a scalp nerve block with just bupivacaine versus bupivacaine plus dexmedetomidine after craniotomy — is a scalp block already part of the standard pain management plan for my surgery, and how does participating in this study differ from what I'd receive otherwise?
2The main thing this trial is measuring is how much morphine I'd need after surgery — what does that mean for my recovery, and are there risks I should know about if I end up needing more or less opioid pain relief than expected?
3This trial is listed as Phase NA, which often means it's testing a procedure or drug combination rather than a new drug on its own — what does that mean for how well the safety and effectiveness of adding dexmedetomidine to the scalp block is understood at this point?
4Since I'd be recovering from brain surgery while also participating in a research study, how would the team monitor my pain and adjust my care if the assigned treatment isn't controlling my pain well enough?
5Are there standard postoperative pain management approaches after craniotomy that don't involve being part of a trial, and how do those compare to what this study is testing, so I can weigh my options with you?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.