CompletedNot Applicable

Comparison of the Effects of Sugammadex and Neostigmine on Early Extubation, Intensive Care Unit Admission and Length of Stay, and Hospital Costs in Adult Cranial Surgery

Turkey (Türkiye)112 participantsStarted 2021-05-01

Plain-language summary

The aim of this study was to retrospectively investigate the effects of sugammadex or neostigmine, which are routinely used after the completion of surgery to antagonize (reverse) neuromuscular blockade in adult patients undergoing cranial surgery under general anesthesia, on early extubation in the operating room, intensive care unit admission and length of stay, length of hospital stay, and hospital costs.

Who can participate

Age range

19 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients from the American Society of Anesthesiology (ASA) I-II-III group, * over the age of 18, * who underwent elective surgery, * underwent general anesthesia with sevoflurane anesthesia from volatile anesthetics, * used rocuronium as a neuromuscular blocking agent Exclusion Criteria: * Patients aged 18 and under, * ASA IV and above, * who underwent surgery under emergency conditions, * who have incomplete follow-up form records and electronic media data, * who were taken to the intensive care unit without neuromuscular blockade antagonism due to long surgery, * who were treated with a neuromuscular blocking agent other than rocuronium, * who were treated with a volatile anesthetic other than sevoflurane or with total intravenous anesthesia.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

The amount of cost in the hospital process

Timeframe: through study completion, an average of 3 month

Length of stay in the intensive care unit

Timeframe: through study completion, an average of 3 month

Early extubation rate after two different neuromuscular blocking antagonist drugs

Timeframe: through study completion, an average of 3 month

Trial details

NCT IDNCT06987357

SponsorKanuni Sultan Suleyman Training and Research Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-07-31

View on ClinicalTrials.gov More Craniectomy trials

Plain-language summary

Who can participate

Age range

19 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

The amount of cost in the hospital process

Timeframe: through study completion, an average of 3 month

Length of stay in the intensive care unit

Timeframe: through study completion, an average of 3 month

Early extubation rate after two different neuromuscular blocking antagonist drugs

Timeframe: through study completion, an average of 3 month