Remineralization Potential of PRG Barrier Coat Versus Fluoride Varnish in White Spot Lesions in P… (NCT06986551) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Remineralization Potential of PRG Barrier Coat Versus Fluoride Varnish in White Spot Lesions in Permanent Anterior Teeth of Children
Egypt78 participantsStarted 2025-09
Plain-language summary
To evaluate the remineralization potential of PRG Barrier Coat versus fluoride varnish in white spot lesions in permanent anterior teeth of children.
Who can participate
Age range
8 Years – 14 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Children aged 8-14 years with good health according to the American Society of Anesthesiologists (ASA-I).
* Have at least one white spot lesion with International Caries Detection and Assessment System (ICDAS II) score one or two
* Has not used any remineralizing agent in the former three months.
* Parents who accept to sign informed consent.
* Cooperative patients
Exclusion Criteria:
* Patients have caries or restorations in the labial surface.
* Extrinsic or intrinsic stains.
* patients under active orthodontic treatment.
* Uncooperative patient.
* Parents refuse to sign informed consent.
* Medically unfit (other than ASAI).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Remineralization potential ΔE: will be recorded by the differences in color perception by Spectrophotometer