The aim of this study is to observe specimens of bronchoalveolar lavage fluid from patients using a reflection enhanced dark-field scattering microscopy. By observing parameters such as the size, morphology, scattering intensity, and movement speed of pathogens, combined with the clinical characteristics of patients, a rapid diagnosis of Pseudomonas aeruginosa infection can be made. At the same time, the bronchoalveolar lavage fluid samples of patients infected with Pseudomonas aeruginosa before and after treatment were compared, and the quantity and vitality of Pseudomonas aeruginosa were observed to judge the efficacy of antibiotics.
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The size of pathogens
Timeframe: From enrollment to the end of treatment at 2 weeks
scattering intensity of pathogen
Timeframe: From enrollment to the end of treatment at 2 weeks
movement speed of pathogens
Timeframe: From enrollment to the end of treatment at 2 weeks