By InvitationNot Applicable

Evaluation of Butyrate Effect on Diarrhea

Italy50 participantsStarted 2024-06-15

Plain-language summary

The goal of this clinical trial is to evaluate the effects of a Food Supplement containing calcium butyrate, vitamin D, and zinc, on the variation of intestinal microbiota and prevention of antibiotic-induced diarrhea, in individuals who have been prescribed antibiotic therapy. The main questions it aims to answer is: Does Dibuzin improve the microbiota composition in patients undergoing antibiotic treatment? Does Dibuzin prevent antibiotic-induced diarrhea? Participants will: - take 2 capsules/day of DBZ (1 /morning and 1 /evening, away from meals) for 14 gg. -Visit the clinic two times ( T0 and at the end), collect three fecal samples, and fill out two questionnaires 3 times.

Who can participate

Age range18 Years – 80 Years

SexALL

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Inclusion Criteria: * Subjects undergoing antibiotic therapy * Subjects capable of conforming to the study protocol * Subjects who have given their free and informed consent Exclusion Criteria: * Subjects with untreated food intolerance, i.e. remaining symptomatic despite the withdrawal of the suspected food * Subjects who become unable to conform to protocol * Subjects who are continuously taking contact laxatives Subjects who are treated with pre/probiotics

What they're measuring

Evaluation of the variation of gut microbiota composition (microbiota test)

Timeframe: 9 months

Trial details

NCT IDNCT06982703

SponsorUniversity of Padova

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12-31

View on ClinicalTrials.gov More Antibiotic-associated Diarrhea trials