Powered vs. Manual Toothbrushing in Stage 3-4 Periodontitis (NCT06980714) | Clinical Trial Compass
By InvitationNot Applicable
Powered vs. Manual Toothbrushing in Stage 3-4 Periodontitis
Italy50 participantsStarted 2024-11-01
Plain-language summary
This study compares the effectiveness of powered and manual toothbrushes in reducing gum bleeding and dental plaque in people with stage 3 or 4 periodontitis. All participants are trained to brush for at least two minutes twice a day. The goal is to find out whether using a powered toothbrush leads to better oral hygiene results than a manual one, when brushing time is standardized. The study will measure bleeding and plaque levels at the beginning and over a 6-month period.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults aged 18 to 75 years
* Diagnosis of stage 3 or 4 periodontitis based on clinical and radiographic examination
* Retaining at least 16 natural teeth
* Ability to follow oral hygiene instructions and compliance with the study protocol
* Willingness to refrain from using additional oral hygiene products (e.g., mouthwash, interdental cleaners) during the study
* Ability to provide informed consent
Exclusion Criteria:
* Presence of systemic conditions that may affect oral health (e.g., uncontrolled diabetes, immunocompromised states)
* Pregnancy or breastfeeding
* Ongoing use of antibiotics or other medications that could interfere with gum health
* Severe dental conditions (e.g., tooth mobility \> 2, advanced root resorption)
* Prior use of a powered toothbrush within the last 6 months
* Participation in another clinical trial that could interfere with study outcomes
* Inability or unwillingness to comply with study requirements or provide informed consent
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Full-Mouth Bleeding Score (FMBS)
Timeframe: FMBS will be assessed at baseline and at 7 days, 1 month, 3 months, and 6 months following the intervention.