Active — Not RecruitingPhase 2/3

Efficacy and Safety of Topical Amphotericin B Solution in Treatment of Resistant Tinea Capitis in Children 16 Years Old or Less we Follow up Cases Weekly up to 8 Weeks and Notice Improvement of Itching ,Scaling, and Hair Regrowth Then Fungal Culture Done to See if the Solution Working

Egypt30 participantsStarted 2025-04-01

Plain-language summary

The goal of this clinical trial is to learn if topical amphotericin b solution works to treat resistant cases of tinea capitis in children. It will also learn about the safety of drug. The main questions it aims to answer are: Does amphotericin b solution effective in cases not cured by systemic antifungal tab? Participants will: use topical amphotericin b solution every day for8 weeks Visit the clinic once every 1 week for follow up then follow up after 1 month and fungal culture will be done to test if the treatment working

Who can participate

Age range0 Days – 16 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Children aged \< 16 years affected by tinea capitis non inflammatory type who are clinically and dermoscopically confirmed after resistant response to oral systemic treatment for 8 weeks. Exclusion Criteria: * Patients with inflammatory tinea capitis, kerion or favus. Patients with known hypersensitivity to amphotericin B, other systemic conditions or ongoing use of conflicting medications.

What they're measuring

monitoring for reduction in size of scaling weekly for 8 weeks

Timeframe: 4 months

Trial details

NCT IDNCT06980493

SponsorSohag University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-06-01

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