By InvitationNot Applicable

A Registered Observational Cohort Study of Myotonic Dystrophy Type 1

China300 participantsStarted 2008-01

Plain-language summary

Myotonic dystrophy type 1 (DM1) is the most common form of muscular dystrophy.There is little phenotype and genetic data for Chinese DM1 patients. The data to be collected is intended to fill this gap and provide complementary data

Who can participate

SexALL

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Inclusion Criteria: * Male or female subjects of all ages at baseline * Subjects, with or without symptoms, with DM1 genetic confirmation through triplet-primed PCR or long-read sequencing * Unrelated healthy controls Exclusion Criteria: * Decline to participate * Other neuromuscular disease (such as Limb-girdle muscular dystrophy or Oculopharyngodistal Myopathy) * Serious systemic illness (such as heart, liver, kidney disease or major mental illness)

What they're measuring

Triplet-primed PCR or Long-read sequencing

Timeframe: Baseline

Muscle Impairment Rating Scale (MIRS)

Timeframe: Baseline through study completion (an average of 1 year)

The modified Medical Research Council (MRC) scale

Timeframe: Baseline through study completion (an average of 1 year)

Trial details

NCT IDNCT06979024

SponsorFirst Affiliated Hospital of Fujian Medical University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2038-12

View on ClinicalTrials.gov More Myotonic Dystrophy Type 1 (DM1) trials