CompletedNot Applicable

Infusion of Dexmedetomidine Versus Lidocaine in Management of Acute Postoperative Pain After Modified Radical Mastectomy

Egypt40 participantsStarted 2025-05-15

Plain-language summary

This study aims to compare the effect of intraoperative intravenous infusion of dexmedetomidine and lidocaine in the management of acute postoperative pain after mastectomy.

Who can participate

Age range18 Years – 65 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age from 18 to 65 years. * American Society of Anesthesiology (ASA) physical status II. * Body mass index (BMI) 18.5-35 kg/m2. * Scheduled for modified radical mastectomy. Exclusion Criteria: * Patient's refusal. * Contraindication to the use of local anesthetics. * Cardiovascular disease. * Significant renal/hepatic impairment * Insulin-dependent diabetes mellitus. * Central nervous system or psychiatric disease. * Use of opioids/steroids/clonidine/other α2 agonist/analgesics or any drugs acting on the central nervous system during the previous 2 weeks. * Drug/alcohol abuse. * Inability to comprehend the pain assessment scale.

What they're measuring

Time to the 1st rescue analgesia

Timeframe: 48 hours postoperatively

Trial details

NCT IDNCT06974656

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-08-20

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