Investigation of a Patient Support Intervention for Statin Medication Adherence (NCT06972979) | Clinical Trial Compass
By InvitationNot Applicable
Investigation of a Patient Support Intervention for Statin Medication Adherence
United States2,200 participantsStarted 2026-04-20
Plain-language summary
Statins have been demonstrated to significantly reduce the risk of cardiovascular disease, but adherence to these medications is suboptimal. Improving adherence can be challenging because it is multifactorial and behaviors often occur within the everyday lives of patients and are less addressable during a visit with a clinician. In this study, the investigators will conduct a randomized trial to evaluate a behaviorally-designed gamification intervention with remote nursing support to improve statin adherence.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults, age 18 and older
* Have a phone or email on file to receive outreach to participate in the study
* Have a primary care provider (PCP) employed by Ascension.
* Prescribed a statin medication and had filled two statin prescriptions in the previous 12 months (one in the prior 6 months and another in the previous 6 to 12 months)
* PDC \<80% in the prior 12 months
* Have consented for electronic communications with Ascension
Exclusion Criteria:
* Patients will be excluded if they do not meet our inclusion criteria.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is focused on improving how consistently people take their statin medication — is my own statin adherence something you think I could realistically improve, and would a structured support intervention like the one in this study be useful for someone in my situation?
2Since this study is 'enrolling by invitation,' how would someone like me actually get considered for it, and is it something you or this practice could refer me into?
3The trial is measuring statin adherence at a population level rather than tracking individual patient health outcomes like heart attacks or cholesterol levels — does that mean I shouldn't expect it to tell us whether statins are actually working better for me personally, and what would you use to judge that instead?
4If I'm already struggling to take my statin consistently, are there strategies or tools available to me right now outside of this trial that might help, or would waiting to see if I could join this study be worth it?
5Since this is a Phase NA behavioral support study rather than a drug trial, what are the main things you'd want me to think about before deciding whether participating fits my schedule and current treatment plan?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.