Moringa Oleifera vs Sodium Hypochlorite for Root Canal Irrigation in Nonvital Primary Molars (NCT06971055) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Moringa Oleifera vs Sodium Hypochlorite for Root Canal Irrigation in Nonvital Primary Molars
Egypt38 participantsStarted 2025-07-20
Plain-language summary
This randomized clinical trial aims to evaluate and compare the antimicrobial efficacy of Moringa Oleifera leaf extract versus sodium hypochlorite as root canal irrigants in pulpectomy of nonvital primary molars in pediatric patients. The study will assess bacterial reduction using blood agar
Who can participate
Age range
4 Years – 7 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Children aged 4 to 7 years
* Clinically and radiographically diagnosed with nonvital primary molars requiring pulpectomy
* Cooperative children who can undergo dental treatment
* Healthy-appearing children with no systemic, physical, or mental disorders
Exclusion Criteria:
* Medically compromised or uncooperative children
* Primary molars indicated for extraction due to:
* Advanced root resorption (more than two-thirds)
* Teeth near exfoliation
* Deep subgingival caries preventing proper restoration
* Excessive mobility (Miller's Grade 2 or higher)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Zone of inhibition against Coagulase-Negative Staphylococci
Timeframe: "Day 1 (Pre- and post-irrigation samples collected during the same visit)"
Trial details
NCT IDNCT06971055
SponsorCairo University
Sponsor typeOTHER
Study typeINTERVENTIONAL
Primary completion2025-09-15
Contact for this trial
Alawi Taha Alaidarous T Principal Investigator, BDS