This prospective cross-sectional case-control study aims to investigate the relationship between serum vitamin D levels, visceral adipose tissue (VAT) thickness, and metabolic parameters in adolescents diagnosed with polycystic ovary syndrome (PCOS), compared to healthy controls. The study includes 70 adolescents with PCOS and 40 age-matched healthy adolescents, all aged between 12 and 19 years, who attended the adolescent gynecology outpatient clinic of a tertiary care hospital. Serum 25-hydroxy vitamin D \[25(OH)D\] levels, fasting glucose, fasting insulin, lipid profiles, anthropometric measurements, and ultrasound-based VAT thickness were assessed. The study seeks to explore potential associations between vitamin D deficiency and metabolic dysregulation in adolescent PCOS patients and to better understand the early cardiometabolic risks associated with PCOS during adolescence.
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Serum 25(OH)D Level at Baseline
Timeframe: At enrollment
Body Mass Index (BMI) at Baseline
Timeframe: At enrollment
HOMA-IR Value at Baseline
Timeframe: At enrollment
Serum Lipid Profile at Baseline
Timeframe: At enrollment
Visceral Adipose Tissue Thickness, Subcutaneous Adipose Tissue Thickness
Timeframe: At enrollment