Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery

Inclusion Criteria: * English-speaking * elective non-cardiac or non-intracranial surgery requiring at least a 2-day hospital length of stay Exclusion Criteria: * Received investigational drug within the last 7 weeks * lack of capacity to provide informed consent * prior known intolerance or allergy to SSRIs or fluvoxamine * planned postoperative ventilation * drug or alcohol dependence * preoperative use of non-NSAID medications with drug-drug interactions of Class X (Avoid Combination) or D (Consider Therapy Modification) * risk of serotonin syndrome (St John's Wort, SSRIs, or TCA)