Sleep, Glucose, and Brain Health in Obesity and Overweight Individuals (NCT06968728) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Sleep, Glucose, and Brain Health in Obesity and Overweight Individuals
400 participantsStarted 2025-05-15
Plain-language summary
The primary aim of the NNF study is to investigate both cross-sectional and longitudinal associations between sleep patterns-measured over two consecutive weeks at baseline and again one year later-and indicators of glycemic control and brain health in a cohort of middle-aged adults. Through this effort, the investigators hope to identify potential sleep-related biomarkers and behavioral targets for early intervention to support metabolic and cognitive health.
Who can participate
Age range
40 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
* Be between 40 and 65 years of age
* Be classified as having normal weight, overweight, or obesity
* Not be pregnant
* Not be currently using glucose-lowering medications or undergoing glucose therapy
* Not have a diagnosis of type 1 or type 2 diabetes mellitus
* Not have kidney disease, thyroid disorders, or inflammatory bowel disease
* Not have undergone bariatric surgery
* Not actively participating in a weight-loss diet
* Not using medications that affect glucose levels or taking sleep-inducing pills
* Not working night shifts
* Not have traveled across time zones in the past 3 months
* Not have any severe chronic medical illnesses or severe psychiatric disorders
* Be able and willing to wear all required study monitoring devices
* Own a smartphone with Bluetooth capability
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Correlation between objective sleep health status and 24-hour glycemic variability
Timeframe: 4 years
2
Correlation Between Sleep Patterns and Brain Health