CompletedNot Applicable

Effect of Trendelenburg Positioning on Anesthesia-Induced Hypotension in Elderly Patients

China168 participantsStarted 2025-05-16

Plain-language summary

This study investigated the effect of Trendelenburg position on preventing post-induction hypotension in elderly patients undergoing abdominal surgery with general anesthesia. The patients will receive the 10° Trendelenburg position or supine position during anesthesia induction. The primary outcome is the area under a mean arterial pressure (MAP) below 65 mm Hg within the first 15 minutes during anesthesia induction.

Who can participate

Age range65 Years – 90 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patients aged 65-90 years * scheduled for abdominal surgery with general anesthesia * expected to have continuous radial arterial pressure monitoring * American Society of Anesthesiologists (ASA) physical status I to III Exclusion Criteria: * contraindications or failure of radial arterial catheterization * expected possible difficult airway * non-sinus rhythm * increased intracranial pressure * patients at high risk of regurgitation or aspiration * inability to provide consent

What they're measuring

The area under the curve of the mean arterial pressure being lower than 65 mmHg

Timeframe: within 15 minutes after anesthesia induction

Trial details

NCT IDNCT06968091

SponsorZhejiang Cancer Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-04-01

View on ClinicalTrials.gov More Hypotension on Induction trials