Perfusion Index in Pediatric Low-Flow Anesthesia (NCT06967675) | Clinical Trial Compass
RecruitingNot Applicable
Perfusion Index in Pediatric Low-Flow Anesthesia
Turkey (Türkiye)90 participantsStarted 2025-06-15
Plain-language summary
This study aims to evaluate changes in perfusion index (PI) in pediatric patients undergoing elective surgery under low-flow anesthesia. PI will be monitored at multiple intraoperative and postoperative time points to assess its relationship with hemodynamic stability and depth of anesthesia. The study will also investigate whether low-flow anesthesia affects the incidence of emergence agitation (EA). Patients will be assigned to either low-flow or normal-flow anesthesia groups based on routine clinical practice. No intervention will be applied beyond standard care. The findings are expected to provide insight into the predictive value of PI in postoperative recovery and support safer anesthesia practices in pediatric populations.
Who can participate
Age range
2 Years – 12 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* ASA I-II pediatric patients
* Age 2 to 12 years
* Undergoing elective surgery lasting between 1-6 hours
* Informed consent obtained from parents/guardians
Exclusion Criteria:
* Cardiovascular, respiratory, neurological, metabolic, or endocrine disorders
* Premature birth with corrected age \< 2 years
* Obesity or severe malnutrition (BMI \<5th or \>95th percentile)
* Psychiatric or neurodevelopmental disorders (e.g., autism)
* Malignant hyperthermia or hypersensitivity to anesthetics
* Emergency surgeries
* Lack of IV access requiring inhalational induction
* Contraindications to low-flow anesthesia including:
* Severe pulmonary disease
* Congenital heart disease with shunt physiology
* Anticipated high oxygen demand
* Airway obstruction risk
* Surgeries requiring high gas flow or \>6 hours duration
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Perfusion Index (PI)
Timeframe: From induction to 30 minutes after extubation