Evaluation of Cold Plasma in Chronic Wound Healing

Inclusion Criteria: * Adult patient, age ≥ 18 years, * Patients affiliated with a social security system or benefiting from such a system, * Patients able and willing to provide written informed consent, * Patients able and willing to attend regular follow-up visits during up to 20 weeks, and comply with study procedures, * Patients whose home healthcare professional is willing to follow the clinical investigation protocol, * Patient with gas conformed stockage area (ventilated or at least 7m²) * Patients without infection, or with a local controlled infection, * Patients with VLU: * Patients with wound anteriority between 1 to 12 months * Patients with VLU or mixed ulcer of predominantly venous origin (measured ankle brachial index (ABI) such as 1.3 ≥ ABI ≥ 0.8) * Patients with VLU between 4 to 30 cm² in surface area, * Patients with only one VLU, * Patients who have not shown wound healing improvement after wearing compression system for at least two weeks * Patients with DFU: * Patients with wound duration between 1 to 12 months * Patients with DFU and with measured ABI ≥ 0.8 or Toe Brachial Index (TBI) ≥ 0.7 * Patients with DFU between 1 to 30 cm² in surface area, * Patients with only one DFU, not between toes, * Patients who have not shown wound healing improvement after wearing an offloading system for at least two weeks, * Patient with PU: * Patient with wound duration between 1 to 12 months * Patient with PU stage 2 or 3 NPUAP grade, * Pa…