We will test the hypothesis that increasing skin wetness, and thus evaporative cooling, will attenuate the increase in core body temperature and accompanying cardiac stress during heat wave conditions in individuals with congestive heart failure. Secondly, we propose that wearing a water-saturated T-shirt will also be beneficial to attenuate the increase in core body temperature and accompanying cardiac stress during heat wave conditions in individuals with congestive heart failure. To accomplish these objectives, individuals with congestive heart failure and otherwise healthy control individuals will be exposed to the simulated heat wave condition (hot and dry) with the following cooling modalities: A) control trial (no limb immersion or skin wetting), B) skin wetting only trial, and C) water-saturated T-shirt trial in a randomized crossover fashion. Thermoregulatory and cardiovascular responses will be evaluated throughout these simulated heat wave exposures. Primary outcomes variables will be skin and core temperatures, while secondary variables will include measures of cardiovascular stress, myocardial perfusion, heart rate, and echo-based measures of cardiac function.
Age range
45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Change in Core Body Temperature while wearing a water-saturated T-shirt
Timeframe: Prior to and after each simulated heat wave exposure (approximately 210 minutes.)
Change in Core Body Temperature in Skin-Wetting Trial
Timeframe: Prior to and after each simulated heat wave exposure (approximately 210 minutes.)
Change in Core Body Temperature in Control Trial
Timeframe: Prior to and after each simulated heat wave exposure (approximately 210 minutes.)
Change in Skin Temperature in while wearing a water-saturated T-shirt
Timeframe: Prior to and after each simulated heat wave exposure (approximately 210 minutes.)
Change in Skin Temperature in Skin-Wetting Trial
Timeframe: Prior to and after each simulated heat wave exposure (approximately 210 minutes.)
Change in Skin Temperature in Control Trial
Timeframe: Prior to and after each simulated heat wave exposure (approximately 210 minutes.)