Effect of L-carnitine on Disease Activity in Patients With Mild to Moderate Knee Osteoarthritis (NCT06960694) | Clinical Trial Compass
CompletedPhase 2
Effect of L-carnitine on Disease Activity in Patients With Mild to Moderate Knee Osteoarthritis
Bangladesh66 participantsStarted 2025-06-28
Plain-language summary
The purpose of this study is to evaluate the effects of L-carnitine on symptomatic improvement, oxidative stress, and inflammation in mild to moderate knee osteoarthritis patients.
Who can participate
Age range40 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Knee pain
* Radiographic evidence of mild to moderate knee osteoarthritis (Kellgren-Lawrence Grade: II-III)
* Above 40 years
* Both male and female
Exclusion Criteria:
* Chronic kidney disease or chronic liver disease
* Diagnosed with systemic inflammatory disorders, such as rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease, gout
* Patients on immunosuppressant treatment
* Any history of intra-articular corticosteroid injections during the previous 2 months
* A history of knee surgery or trauma
* Any antioxidant vitamins use, such as A, C, and E, or history of use in the last two months
* History of taking L-carnitine and NSAIDs in last 2 months
* Pregnancy or lactation
* Participation in another clinical trial
What they're measuring
1
Pain, stiffness and physical function
Timeframe: 8 weeks
Trial details
NCT IDNCT06960694
SponsorBangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh