Resistance Exercise Training on Vascular and Physical Function in Postmenopausal Women (NCT06958965) | Clinical Trial Compass
CompletedNot Applicable
Resistance Exercise Training on Vascular and Physical Function in Postmenopausal Women
Taiwan32 participantsStarted 2025-06-09
Plain-language summary
Postmenopausal women often face risks of vascular dysfunction and muscle deterioration due to estrogen deficiency. These changes significantly increase the risk of cardiovascular disease and mortality. Previous studies have shown a significant positive correlation between vascular endothelial function and muscle strength. Moreover, muscle strength is a stronger predictor of mortality than muscle mass and is closely associated with the maintenance of functional independence in daily life. However, studies investigating the effects of whole-body progressive resistance training on vascular function and physical performance in postmenopausal women remain limited. This study aims to examine changes in vascular function and muscle strength in postmenopausal women following a whole-body progressive resistance training program.
Who can participate
Age range
55 Years – 70 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Postmenopausal women aged between 55 and 70 years;
. Body mass index (BMI) less than 30 kg/m²;
. At least one year since menopause;
. Able to live independently in the community;
. Able to communicate independently in Mandarin or Taiwanese.
Exclusion criteria
. Acute musculoskeletal injuries within the past month (e.g., acute inflammation, fractures, sprains, contusions, or joint implants);
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Flow-mediated dilation-endothelial function
Timeframe: Change from baseline at 12 weeks
2
Brachial-ankle plus wave velocity (baPWV)-arterial stiffness
. Diagnosed central or peripheral nervous system disorders affecting exercise participation (e.g., stroke, dementia, Parkinson's disease, autonomic dysfunction);
. History of serious cardiac conditions within the past six months (e.g., coronary stenting, pacemaker implantation, peripheral or cerebral vascular reconstruction);