Rate of Allergic Contact Dermatitis and Cosmetic Outcomes (NCT06957444) | Clinical Trial Compass
By InvitationNot Applicable
Rate of Allergic Contact Dermatitis and Cosmetic Outcomes
United States600 participantsStarted 2025-10-13
Plain-language summary
The patients from the Department of Orthopaedics Center for Joint Replacement will be asked to participate in the study. These patients will be randomized to one of three wound closure products, Sylke adhesive dressing, Exofin skin glue, or Suture Strip Plus. Participants will be asked to take a photograph of the incision 4 days after surgery to submit via MyChart for review by the WVU Department of Dermatology Team. All patients will be evaluated at their regular 2-week, 6-week, and 3-month post-operative visits where clinical photographs will be submitted for independent review by the WVU Department of Dermatology Team to assess outcomes.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Willing and able to sign the informed consent
* Patients presenting to the WVU Medicine Center for Joint Replacement who have a primary TKA or THA surgery scheduled
* Patients with surgical wounds closed by 2-0 vicryl and barbed, running v-loc suture (assessed in OR)
* Active MyChart account and the ability to take and upload a photo in that system
Exclusion Criteria:
* Patients scheduled for a revision THA or revision TKA
* THA used for treatment of a fracture
* Patients participating in other studies that might have involve medications such as antibiotics
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Since this trial is specifically tracking allergic contact dermatitis after hip or knee surgery, can you explain what product or material used during my procedure might cause this skin reaction, and why measuring it is important for my care?
2This trial follows patients at 4 days, 2 weeks, 6 weeks, and 3 months after surgery — how would participating affect my follow-up schedule compared to what I'd have with standard post-operative care?
3Since enrollment is by invitation only, what criteria are used to select patients, and is there a reason my care team would or wouldn't consider me for this study?
4If I do develop allergic contact dermatitis during the study period, how would that be managed, and would it affect my recovery from the hip or knee osteoarthritis surgery itself?
5Are there standard surgical or wound-care options that don't involve whatever is being studied here, and would choosing one of those alternatives change the quality of my osteoarthritis treatment outcome?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Rate of allergic contact dermatitis (4 Days Post Op)
Timeframe: 4 Days Post-Op
2
Rate of allergic contact dermatitis (2 Weeks Post Op)
Timeframe: 2 Weeks Post-Op
3
Rate of allergic contact dermatitis (6 Weeks Post Op)
Timeframe: 6 Weeks Post-Op
4
Rate of allergic contact dermatitis (3 Months Post Op)