RecruitingNot Applicable

3D MRE-Based Evaluation of Meningioma Mechanical Properties and Histological Features

China300 participantsStarted 2022-10-19

Plain-language summary

This prospective single-center study aims to evaluate the feasibility and clinical utility of three-dimensional magnetic resonance elastography (3D MRE) in assessing tumor stiffness and adhesion in patients with meningioma undergoing surgical resection. By correlating preoperative MRE-derived stiffness and adhesion maps with intraoperative findings and histopathological features, the study seeks to determine whether MRE can serve as a noninvasive imaging biomarker for surgical planning, risk stratification, and prediction of tumor behavior.

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All patients undergoing meningeoma resection surgery are eligible for inclusion in the study cohort. Exclusion Criteria: * Patients with metallic implants or foreign bodies in their bodies (pacemakers, artificial metallic heart valves, metal joints, metal implants, and those who can not remove dentures, insulin pumps, or contraceptive rings) * Pregnant women in the first trimester (within three months) * Patients with severe claustrophobia or anxiety * Patients with severe fever * Patients who can not tolerate MRE * Patients with vascular malformations and aneurysms. * Patients who do not sign an informed consent

What they're measuring

Agreement Between MRE Stiffness and Intraoperative Tumor Consistency

Timeframe: Intraoperative (Day of Surgery)

Trial details

NCT IDNCT06955208

SponsorShengjing Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-10-09

Contact for this trial

Yu Shi, MD

+86 189 4025 9980 18940259980@163.com

View on ClinicalTrials.gov More Meningioma trials