RecruitingNot Applicable

Restricted Versus Liberal Fluid Intake for Prevention of Bronchopulmonary Dysplasia

Switzerland750 participantsStarted 2025-07-12

Plain-language summary

The aim of this study is to determine whether restricted fluid intake (135 ±5 mL/kg/day) compared to liberal fluid intake (165 ±5 mL/kg/day) from day 8 of life reduces the incidence of bronchopulmonary dysplasia (BPD) at 36 weeks postmenstrual age or prior death in preterm infants born \<30 weeks gestational age.

Who can participate

Age range8 Days

SexALL

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Inclusion Criteria: * Hospitalised preterm infants born before 30 weeks 0 days gestation * Signed informed consent for further research use of health-related data Exclusion Criteria: * congenital malformations * diseases likely to affect life expectancy, lung function, fluid strategy, or neurodevelopment * renal disease requiring fluid management outside the clinical standard of care * congenital heart disease not including patent ductus arteriosus (PDA)

What they're measuring

Bronchopulmonary dysplasia (BPD)

Timeframe: From enrolment to 36 weeks postmenstrual age

Trial details

NCT IDNCT06954142

SponsorUniversity Children's Hospital Basel

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2029-12

Contact for this trial

Anne Carrer

+4161 704 2853 anne.carrer@ukbb.ch

View on ClinicalTrials.gov More Bronchopulmonary Dysplasia trials