Not Yet RecruitingNot Applicable

Ultrasound Guided Stellate Ganglion Block in Postural Tachycardia Syndrome

United States20 participantsStarted 2025-10-13

Plain-language summary

This single-center study aims to evaluate both immediate and long-term outcomes of stellate ganglion block (SGB) in a cohort of rigorously phenotyped patients with Postural Tachycardia Syndrome (POTS). By assessing the effects of SGB, this study seeks to determine its viability as an intervention for symptom control in POTS.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult patients (\>18 years of age) diagnosed with POTS * Ability to provide informed consent * Ability to comply with 3 follow up visits * English speaking and capable of signing informed consent and complying with protocol requirements Exclusion Criteria: * Allergy to local anesthetics * Severe coagulopathy * History of or currently being treated for clinically significant ongoing cardiac arrhythmia, heart failure, myocarditis, pulmonary embolism requiring anticoagulation, pulmonary fibrosis or other pulmonary diagnosis that in the investigator's opinion may contribute to symptoms of POTS * Inability to maintain a stable medication regiment for the duration of the study

What they're measuring

COMPASS 31 total score

Timeframe: Baseline (day -21 to -1 before intervention), first follow-up (day 1 to 21 after the intervention) and second follow-up (day 74 to 94 after the intervention)

Trial details

NCT IDNCT06953661

SponsorStanford University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-11

Contact for this trial

Anna Maria Bombardieri, MD, PhD

3143269107 abomba@stanford.edu

View on ClinicalTrials.gov More Postural Tachycardia Syndrome trials