RecruitingNot Applicable

Investigating Periprosthetic Fracture Cultures in Arthroplasty

United States200 participantsStarted 2025-10-01

Plain-language summary

This study aims to improve how doctors diagnose infections in patients with broken bones around joint replacements. Currently, there are no clear guidelines to help determine when an infection is present, making treatment decisions difficult. By studying how often infections are found through lab tests and identifying factors that predict infection, the investigators hope to create better ways to diagnose and care for these patients.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult patients (\>18 years old) with periprosthetic fractures around primary or revision hip or knee arthroplasty * Patients requiring operative management for these fractures (fixation or revision arthroplasty) * Patients presenting to the University of Chicago Medical Center during two (2) year period (October 2025 to October 2027) Exclusion Criteria: * Patients undergoing non-operative management for periprosthetic fractures * Any documented or reported history of past prosthetic joint infection of the involved joint * Sinus tract at the time of presentation at the involved joint

What they're measuring

Culture Positivity Rates

Timeframe: From enrollment to the end of treatment at 14 days.

Trial details

NCT IDNCT06952738

SponsorUniversity of Chicago

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-04-30

Contact for this trial

Malik J Scott, BA

773-834-0822 mjscott1@uchicago.edu

View on ClinicalTrials.gov More Periprosthetic Fracture Around Prosthetic Joint Implant trials