Ultrasound Perfusion Estimation for Assessment of Peripheral Arterial Disease (NCT06952543) | Clinical Trial Compass
RecruitingNot Applicable
Ultrasound Perfusion Estimation for Assessment of Peripheral Arterial Disease
United States400 participantsStarted 2025-03-14
Plain-language summary
The purpose of this study is to develop a new noninvasive tool for early diagnosis of Peripheral Arterial Disease (PAD) and use the proposed method for monitoring the disease progression and the response to interventional treatment in PAD patients.
Who can participate
Age range
18 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Patient volunteers:
* Male and Female, ages 18 years old and up
* Symptom of claudication and suspected for PAD
* Scheduled for vascular testing.
Healthy volunteers:
* Male and female, ages 18-75 years old and up
* Normal BMI
* No history of smoking, cardiovascular disease, or diabetes.
Exclusion Criteria:
Patient volunteers:
* Patients with gangrene
* Patients having surgery or stent
* Patients with ulcer on their leg
* Any health condition that does not allow proper use of ultrasound scanning
* People considered in "vulnerable" populations.
Healthy volunteers:
* Include volunteers with BMI not more than 30
* No history of smoking
* No history of (diabetes, hypertension, cardiovascular diseases)
* People considered in "vulnerable" populations.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Detection of peripheral arterial disease using ultrasound perfusion estimation