The Effect of Molar Incisor Hypomineralisation on the Stomatognathic System (NCT06951139) | Clinical Trial Compass
CompletedNot Applicable
The Effect of Molar Incisor Hypomineralisation on the Stomatognathic System
Turkey (Türkiye)84 participantsStarted 2025-03-10
Plain-language summary
This study aims to examine whether children with Molar Incisor Hypomineralization (MIH) are more likely to have problems with the jaw joint and chewing muscles. MIH is a dental condition where the enamel of the first molars and incisors is weaker than normal. The researchers performed clinical examinations and ultrasound imaging to evaluate the thickness and elasticity of the chewing muscles. They also used a questionnaire to check for symptoms of temporomandibular disorders (TMD), such as jaw pain, headaches, and joint sounds.
Who can participate
Age range
9 Years – 14 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Children aged between 9 and 14 years
* Good general health with no systemic disease
* Score of 3 or 4 on the Frankl Behavior Rating Scale
* No parafunctional oral habits (e.g., bruxism)
* No skeletal orthodontic abnormalities
* For the MIH group: presence of at least one first permanent molar diagnosed with MIH
* For the control group: absence of MIH diagnosis
Exclusion Criteria:
* Presence of advanced periodontal disease or tooth mobility
* History of facial trauma or jaw fracture
* Current medication use
* Inability to cooperate during clinical or ultrasonographic examinations
* Any condition that may affect temporomandibular joint structure or function
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Prevalence of temporomandibular disorders (TMD) in children with MIH
Timeframe: At the time of enrollment (single clinical visit)
2
Thickness of masticatory muscles in children with and without MIH
Timeframe: At the time of enrollment (single clinical visit)
3
Elasticity of masticatory muscles in children with and without MIH
Timeframe: At the time of enrollment (single clinical visit)