Time-of-Day Effects of Fasted Exercise on Energy Intake (NCT06947824) | Clinical Trial Compass
CompletedNot Applicable
Time-of-Day Effects of Fasted Exercise on Energy Intake
Germany35 participantsStarted 2025-04-01
Plain-language summary
This trial's aim is to investigate the time-of-day effects (morning vs. evening) of fasted exercise on acute and 24h post-exercise energy intake. Specifically, we will compare the effects of fasted morning exercise (12h overnight fast) vs. fasted (6h and 12h) evening exercise on total energy intake during a post-exercise ad libitum test meal as well as on 24h (free-living) energy intake. The secondary aim is to assess subjective appetite ratings before, immediately after, and 30 min post-exercise (visual analog scale). Healthy men and women aged 18-30 years will be included.
Who can participate
Age range
18 Years – 30 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* BMI of 18.5.0-30.0 kg/m2
* weight stability (≤2.5 kg weight change during the past 3 months)
* ability to exercise at a vigorous intensity for 30 minutes
Exclusion Criteria:
* pregnancy or breastfeeding
* smoking
* history of or current eating disorders
* medical condition or use of medication that could affect appetite or pose any contraindications to exercise
As the menstrual cycle can cause fluctuations in food cravings and appetite, women of childbearing age were only eligible if they used hormonal contraceptives. To ensure constant exposure to exogenous estrogen and progestin throughout the study phase, participating women were further asked to use active hormone pills throughout the study period in both studies, a practice that is considered both safe and efficacious.
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Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Acute ad-libitum post-exercise energy intake (test meal)