CompletedNot Applicable

Comparing Exposure v Imagery Rescripting in People With OCD: a SCED

United Kingdom6 participantsStarted 2024-08-30

Plain-language summary

Individuals with OCD may experience intrusive future orientated thoughts and images, which are extremely distressing and interfering in life. This project aims to explore whether imagery rescripting or exposure may be a more effective intervention for individuals with OCD experiencing such images.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18 years or over * Main diagnosis of OCD (assessed by the Structured Clinical Interview for ICD11) * Must report future orientated images that are distressing and ego-dystonic Exclusion Criteria: * Psychosis, bipolar disorder, or trauma disorder * Current stimulant or hallucinogenic misuse, alcohol or substance misuse or dependence * Intellectual disability, dementia, serious cognitive impairment, or organic brain disorder * Personality Disorder as the main problem * Active suicidality * Concurrent engagement in other psychotherapy * A patient may be taking anti-depressant medication so long as the dose has been stable for 6 weeks and there is no plan to increase the dose.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Obsessive Compulsive Inventory (OCI).

Timeframe: From the start of treatment until the end of treatment at 12 weeks.

Yale-Brown Obsessive-Compulsive scale (Y-BOCS).

Timeframe: From the start of treatment until the end of treatment at 12 weeks.

The Impact of Future Events Scale (IFES).

Timeframe: From the start of treatment until the end of treatment at 12 weeks.

The Florida Obsessive Compulsive Inventory (FOCI).

Timeframe: From the start of treatment until the end of treatment at 12 weeks.

Visual Analogue Scales (VAS).

Timeframe: From the start of treatment until the end of treatment at 12 weeks.

Trial details

NCT IDNCT06944366

SponsorKing's College London

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-04-30

View on ClinicalTrials.gov More Obsessive-Compulsive Disorder (OCD) trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Obsessive Compulsive Inventory (OCI).

Timeframe: From the start of treatment until the end of treatment at 12 weeks.

Yale-Brown Obsessive-Compulsive scale (Y-BOCS).

Timeframe: From the start of treatment until the end of treatment at 12 weeks.

The Impact of Future Events Scale (IFES).

Timeframe: From the start of treatment until the end of treatment at 12 weeks.

The Florida Obsessive Compulsive Inventory (FOCI).

Timeframe: From the start of treatment until the end of treatment at 12 weeks.

Visual Analogue Scales (VAS).

Timeframe: From the start of treatment until the end of treatment at 12 weeks.