Bracing and Reconstruction of the Anterior Cruciate Ligament for Efficacy Trial (NCT06942754) | Clinical Trial Compass
RecruitingNot Applicable
Bracing and Reconstruction of the Anterior Cruciate Ligament for Efficacy Trial
United States96 participantsStarted 2025-09-11
Plain-language summary
Several attempts have been made to reduce these failure rates and improve return to sports rates in high-risk populations, and one of these approaches has been postoperative bracing. A recent survey of the Anterior cruciate ligament (ACL) Study Group has shown that 53% of surgeons prefers functional bracing following ACL reconstruction. Currently, however, there is no clear consensus on whether functional bracing following ACL reconstruction leads to lower failure rates, improved stability or better patient-reported outcomes when compared to ACL reconstruction without bracing.
Who can participate
Age range
14 Years – 39 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* patients with unilateral complete ACL injury
* patients involved in sports and the desire to return to sports
* patients undergoing quadriceps autograft ACL reconstruction
* must be 14 to 39 years old
Exclusion Criteria:
* multiligamentous knee injuries defined as two ligaments requiring surgical stabilization
* concomitant suture tape augmentation, extra-articular tenodesis or anterolateral ligament reconstruction
* concomitant femoral, tibial, or patellar fracture(s)
* patients with significant osteoarthritis
* concomitant ipsilateral knee dislocation or patellar dislocation
* significant lower leg malalignment requiring correcting osteotomies
* prior ACL surgery, including contralateral knee
* pregnancy during injury or surgery
* unable to provide consent
* prolonged use of prednisolone or cytostatics
* comorbidities (e.g., muscular, neurological, vascular) that influence rehabilitation
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in ACL-return to sport index (ACL-RSI) Scores