This study aims to investigate the neurophysiological effects of live music on individuals with early Alzheimer's Disease (AD), dementia, and/or mild cognitive impairment (MCI) and their caregivers. Heart rate (HR), heart rate variability (HRV), and brain activity will be measured as participant-caregiver dyads listen to preferred and improvised music performed by professional musicians. Investigators will leverage various measurement techniques including, but not limited to, electroencephalography (EEG), behavioral, surveys, and physiological monitoring to study the impact of live music on anxiety in AD and inter-dyad synchrony.
Age range
50 Years – 80 Years
Sex
ALL
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Change in EEG activity during live music vs pre-recorded music conditions
Timeframe: Day 1 and Day 2, an average of 1 week apart
motion capture
Timeframe: Day 1 and Day 2, an average of 1 week apart
facial action units
Timeframe: Day 1 and Day 2, an average of 1 week apart
eye gaze
Timeframe: Day 1 and Day 2, an average of 1 week apart
Changes in Standard Deviation of Normal-to-Normal (SDNN) Interval via electrocardiography (ECG, EKG).
Timeframe: Day 1 and Day 2, an average of 1 week apart
Changes in Root Mean Square of Successive Differences (RMSSD) via electrocardiography (ECG, EKG).
Timeframe: Day 1 and Day 2, an average of 1 week apart
Changes in Very low frequency (VLF) via electrocardiography (ECG, EKG).
Timeframe: Day 1 and Day 2, an average of 1 week apart
Changes in the ratio of low frequency and high frequency (LF/HF) via electrocardiography (ECG, EKG).
Timeframe: Day 1 and Day 2, an average of 1 week apart