Pre-Sleep Creatine Enhances Anaerobic Power in Recreationally Active Females (NCT06937190) | Clinical Trial Compass
RecruitingNot Applicable
Pre-Sleep Creatine Enhances Anaerobic Power in Recreationally Active Females
Iran24 participantsStarted 2025-04-01
Plain-language summary
This study is a randomized, double-blind, placebo-controlled trial designed to examine the effects of pre-sleep creatine monohydrate supplementation on anaerobic performance and muscle damage markers in recreationally active females. Participants will be randomly assigned to receive either 5 grams of creatine monohydrate or a placebo 30 minutes before sleep for seven consecutive days. Anaerobic performance will be assessed using the Wingate Anaerobic Test, evaluating peak and average power output and fatigue index. Blood samples will be collected before and after the supplementation period to analyze markers of muscle damage, including creatine kinase and lactate dehydrogenase. This study aims to provide insight into the efficacy of short-term, time-specific creatine supplementation for enhancing performance and recovery.
Who can participate
Age range
18 Years – 25 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Female, aged 18 to 25 years
Recreationally active (engaging in structured resistance training 3-4 times per week for the past 6 months)
Regular menstrual cycles (used for scheduling purposes)
Able and willing to provide informed consent
Agreement to maintain normal diet and training routines throughout the study
Exclusion Criteria:
History of musculoskeletal injury affecting lower or upper limbs within the past 6 months
Known allergy or intolerance to creatine or maltodextrin
Use of performance-enhancing substances or supplements within the last 30 days
Use of recovery modalities such as massage, cryotherapy, or compression garments during the study period
Current use of anti-inflammatory medication
Pregnancy or breastfeeding
Inability to comply with study protocol or scheduled assessments
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Average Power Output (Watts) - 30-Second Wingate Test
Timeframe: Baseline and post-intervention (Day 0 and Day 7)