Oral Melatonin VS Nebulized Dexmedetomidine Premedication on Attenuation of Hemodynamic Response to Direct Laryngoscopy and Tracheal Intubation in Hypertensive Patients

Inclusion Criteria: * Age (40-60) years of both genders. * Controlled hypertensive patients. * Categorized as ASA physical status II. * Planning to do an elective surgery under General Anesthesia. Exclusion Criteria: * Patient refusal to participate in the study. * Patient with expected difficult intubation. * Body Mass Index (BMI) \> 30 kg/m2. * History of allergy to the drugs of the study. * Patients with Heart rate\<50 or Heart block. * End stage renal and hepatic disease. * Patients on beta blocker, oral hypoglycemics, anti-depressants, anti-convulsants, anti- psychotics and thyroid medications. * Pregnant or lactating females.