This observational study examines changes in the median nerve in patients diagnosed with diabetic polyneuropathy (DPN) and carpal tunnel syndrome (CTS) using shear wave elastography, microvascular imaging, and cross-sectional area measurements. It also compares the individual and combined effects of type 2 diabetes mellitus, DPN, and CTS on symptoms and hand function.
Who can participate
Age range18 Years – 78 Years
SexALL
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Inclusion Criteria:
Patient Group:
* Presence of carpal tunnel syndrome (CTS) symptoms, including pain, numbness, tingling, burning, and weakness, which worsen during sleep, prolonged hand positions, or repetitive wrist movements, and improve with hand shaking or changing position.
* Cognitively able to understand and participate in the study.
* Aged between 18 and 78 years.
* Has given written informed consent to participate.
Control Group:
* Asymptomatic individuals, with or without diabetes.
* Cognitively able to understand and participate in the study.
* Aged between 18 and 78 years.
* Has given written informed consent to participate.
Exclusion Criteria:
* History of previous carpal tunnel surgery or injection.
* History of previous upper extremity trauma.
* Presence of mass lesions or any condition that compresses the median nerve, observed during ultrasonographic examination.
* Presence of a persistent median artery.
* Presence of a bifid or trifid median nerve.
* Presence of anastomoses, such as Martin-Gruber.
* History of long-term excessive alcohol consumption.
* Chronic renal failure.
* Presence of neuropathy due to a neurological condition.
* Thyroid disorders.
* History of malignancy.
* History of neurotoxic drug use.
* Peripheral arterial occlusive disease.
* Severe diabetic polyneuropathy (DPN) diagnosis.
* Pregnancy.
* Cervical radiculopathy or brachial plexopathy.
* Osteoarthritis of the hand.
* Rheumatologic disease.
* Systemic autoimmune disease.
* Hi…
What they're measuring
1
Sonographic and symptomatic assessment of median nerve