Not Yet RecruitingNot Applicable

Continuous Assessment of Brain Blood Perfusion in Subarachnoid Hemorrhage Patients Using Near-Infrared Spectroscopy (NIRS)

United States120 participantsStarted 2026-07-01

Plain-language summary

The goal of this observational study is to continuously assess cerebral autoregulation in patients with subarachnoid hemorrhage (SAH) using cerebral oximetry index (COx) and hemoglobin volume reactivity index (HVx). The main question it aims to answer is: Whether optimal perfusion pressure is dynamic and changes with time in patients with SAH, and that autoregulation is disrupted in patients during the course of SAH, contributing to delayed cerebral ischemia (DCI).

Who can participate

Age range18 Years – 89 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients aged 18 to 89 years who are admitted to the Neurological Intensive Care Unit (Neuro ICU) between March 2025 and December 2026 for aneurysmal subarachnoid hemorrhage (SAH). Exclusion Criteria: * Patients under 18 years old * Prisoners * Pregnant women * Patients enrolled in concurrent ongoing interventional trial * Students of UAB * Employees of UAB * Patients who undergoes frontal decompression surgery resulting bone flap deficit where NIRS monitoring pads could not be applied.

What they're measuring

Change in Lower Limit of Autoregulation (LLA)

Timeframe: 21 days

Trial details

NCT IDNCT06932640

SponsorUniversity of Alabama at Birmingham

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2028-06-30

Contact for this trial

LaShun L. Horn, M.S.

205-996-2606 llhorn@uabmc.edu

View on ClinicalTrials.gov More Subarachnoid Hemorrhage, Aneurysmal trials