RecruitingNot Applicable

UNCPM 22322 - Adaption of the Transition of Care Model for Post-Discharge HIV-NCD Care in Lilongwe, Malawi - MLATHO

Malawi75 participantsStarted 2025-05-12

Plain-language summary

This is an implementation research study that will adapt and pilot test the Transitional Of Care Model (TCM), originally conceived and developed in the USA, for targeted use as a post-discharge intervention for adults hospitalized with comorbid HIV and NCDs in Malawi using a mixed methods approach.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18 years of age or older * living with HIV * admitted to internal medicine * has at least a cardiometabolic NCO as the primary or secondary reason for admission based on the HIV inpatient consultation Exclusion Criteria: * patients living beyond Lilongwe urban

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Post-discharge home visits

Timeframe: Through 3-months post-discharge

Completion of comprehensive needs assessment

Timeframe: Through 3-months post-discharge

Feasibility rating from health worker perspective.

Timeframe: At 3 months post-discharge

Feasibility rating from patient and caregiver perspective

Timeframe: At 3 months post-discharge

Reach among eligible hospitalized adults with HIV/NCD comorbidity

Timeframe: At completion of enrollment

Acceptability of Intervention Measures(AIM) rating from patient and caregiver perspective

Timeframe: At 3 months post-discharge

Acceptability of Intervention Measures(AIM) rating from Healthcare Workers perspective

Timeframe: At 3 months post-discharge

Trial details

NCT IDNCT06931431

SponsorUniversity of North Carolina, Chapel Hill

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-03

Contact for this trial

Chimwemwe Chawinga

265884409026 cchawinga@unclilongwe.org.mw

View on ClinicalTrials.gov More HIV trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Post-discharge home visits

Timeframe: Through 3-months post-discharge

Completion of comprehensive needs assessment

Timeframe: Through 3-months post-discharge

Feasibility rating from health worker perspective.

Timeframe: At 3 months post-discharge

Feasibility rating from patient and caregiver perspective

Timeframe: At 3 months post-discharge

Reach among eligible hospitalized adults with HIV/NCD comorbidity

Timeframe: At completion of enrollment

Acceptability of Intervention Measures(AIM) rating from patient and caregiver perspective

Timeframe: At 3 months post-discharge

Acceptability of Intervention Measures(AIM) rating from Healthcare Workers perspective

Timeframe: At 3 months post-discharge