The goal of this observational cohort study is to gain deep insights into how metabolic disorders such as obesity or diabetes during pregnancy affect the metabolic and cardiovascular health of mother and child in the short and long term. It will investigate the following questions: * How do maternal metabolic disorders affect pregnancy outcomes? * How do maternal metabolic disorders affect fetal growth? * How do maternal metabolic disorders affect the newborn's metabolism and body composition? * How do maternal metabolic disorders during pregnancy affect breast milk composition? * How do maternal metabolic disorders during pregnancy affect the metabolic health of the mother after birth? Participants in this study are pregnant women who will be asked to come to the clinics for three visits during their pregnancy, as well as for the delivery of their baby, and one time 2-3 months thereafter. At each visit, researchers will perform physical examinations (such as body composition measurements) and collect biological samples (blood, urine, saliva), clinical information, and lifestyle data. At birth, researchers will collect cord blood and breast milk as well as clinical data of the delivery and the health of the baby. Researchers will measure body fat in newborn babies and at 2-3 months of age.
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Maternal adiposity
Timeframe: From enrolment to 8-12 weeks post partum
Maternal fasting blood glucose
Timeframe: from enrollment to 8-12 weeks postpartum
Maternal blood pressure
Timeframe: From enrolment to 8-12 weeks postpartum
Maternal lipid profiles - triglycerides
Timeframe: From enrolment to 8-12 weeks post partum
Maternal lipid profiles: phospholipids
Timeframe: From enrolment to 8-12 weeks post partum
Maternal lipid profiles: free fatty acids
Timeframe: From enrolment to 8-12 weeks post partum
Maternal lipid profiles: total cholesterol
Timeframe: From enrolment to 8-12 weeks post partum
Maternal lipid profiles: HDL cholesterol
Timeframe: From enrolment to 8-12 weeks post partum
Evelyn Jantscher-Krenn, PhD
Maternal lipid profiles: LDL cholesterol
Timeframe: From enrolment to 8-12 weeks post partum
Maternal endothelial function
Timeframe: From enrolment to 8-12 weeks post partum
Maternal cytokine profile
Timeframe: From enrolment to 8-12 weeks postpartum
Gestational diabetes
Timeframe: From enrolment to child birth; 6 months
Hypertensive disorders of pregnancy
Timeframe: From enrolment to child birth; 6 months
Neonatal body composition at birth
Timeframe: between delivery and 48h postpartum
Neonatal C-peptide in cord blood
Timeframe: at birth
Neonatal cytokine profile
Timeframe: at birth
Neonatal epigenetic profile
Timeframe: at birth