CompletedNot Applicable

Targeted Muscle Reinnervation in the Hand for the Managment of Symptomatic Neuroma Following Digit and Hand Amputations

Egypt17 participantsStarted 2021-08-20

Plain-language summary

Neuromas are a common complication after digital and hand amputations, resulting in significant pain, discomfort, and functional impairment. Various management methods are available, including surgical excision, nerve blocks, and nerve stump protectors, but these treatments may have limited success rates and potential complications. Targeted muscle reinnervation (TMR) is a promising technique that involves surgically rerouting a severed nerve into a nearby muscle, which can prevent the formation of neuromas and provide improved muscle function

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Arabic or English speaking individuals * An upper limb amputation distal to the wrist crease * A symptomatic neuroma within the hand or digits: defined as patient-reported localized pain consistent with a clinical exam of a neuroma pain.There must be a supporting Tinel's sign on physical exam. Exclusion Criteria: * Cognitive impairment for better assessment of patient reported outcomes and filling questionnaires and signing consents

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Neuroma incidence

Timeframe: through study completion, an average of 1 year

Neuroma recurrence

Timeframe: through study completion, an average of 1 year

Pain intensity

Timeframe: will be taken at intervals over time (1 month, 3 months,6 months, 9 months,1 year until the conclusion of the study

Pain medication usage type

Timeframe: Followed up at intervals over time (1 month, 3 months,6 months, 9 months,1 year until the conclusion of the study

Pain medication usage frequency

Timeframe: Followed up at intervals over time (1 month, 3 months,6 months, 9 months,1 year until the conclusion of the study

Pain character

Timeframe: will be taken at intervals over time (1 month, 3 months,6 months, 9 months,1 year until the conclusion of the study

Pain character

Timeframe: will be taken at intervals over time (1 month, 3 months,6 months, 9 months,1 year until the conclusion of the study

Trial details

NCT IDNCT06923566

SponsorAin Shams University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-07-30

View on ClinicalTrials.gov More Targeted Muscle Reinervation trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Neuroma incidence

Timeframe: through study completion, an average of 1 year

Neuroma recurrence

Timeframe: through study completion, an average of 1 year

Pain intensity

Timeframe: will be taken at intervals over time (1 month, 3 months,6 months, 9 months,1 year until the conclusion of the study

Pain medication usage type

Timeframe: Followed up at intervals over time (1 month, 3 months,6 months, 9 months,1 year until the conclusion of the study

Pain medication usage frequency

Timeframe: Followed up at intervals over time (1 month, 3 months,6 months, 9 months,1 year until the conclusion of the study

Pain character

Timeframe: will be taken at intervals over time (1 month, 3 months,6 months, 9 months,1 year until the conclusion of the study

Pain character

Timeframe: will be taken at intervals over time (1 month, 3 months,6 months, 9 months,1 year until the conclusion of the study