Not Yet RecruitingNot Applicable

the Prediction Value of Combined Electroencephalographic and Electromyographic Response in Disorders of Consciousness

36 participantsStarted 2025-04-15

Plain-language summary

The goal of this observation study is to learn about the prediction value of combined electroencephalographic and electromyographic response in disorders of consciousness. The main ways of stimulation is thermal and itch. Six months after inclusion in the study, patients were classified according to the Glasgow Outcome Scale Extended, (GOSE).

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Age ≥18 years.
✓. Brain damage lasts 28 to 90 days.
✓. It meets the diagnostic criteria of unresponsive arousal syndrome/vegetative state (UWS/VS) or microconscious state (MCS).
✓. All subjects' legal guardians sign informed consent forms.

Exclusion criteria

✕. Spinal cord T1 and above plane injury, peripheral nerve injury and so on affect nerve conduction;
✕. The impact of injury on palms and soles of feet;
✕. History of developmental, psychiatric, or neurological disorders prior to brain injury.
✕. Deep sedation within 72 hours, including the use of general anesthesia.
✕. Increased intracranial pressure, liver/kidney failure, and hemodynamic instability within 72 hours.
✕. Severe co-existing systemic diseases with limited life expectancy.

What they're measuring

the state of consciousness

Timeframe: 6 months

Trial details

NCT IDNCT06922864

SponsorKY20242235jiangwen

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-12-31

Contact for this trial

+86+15399059833 304517021@qq.com

View on ClinicalTrials.gov More Disorders of Consciousness Due to Severe Brain Injury trials