Not Yet RecruitingNot Applicable

Study of Auditory Perception After Progressive Exposure to Aversive Sounds in People With Misophonia

France110 participantsStarted 2025-06

Plain-language summary

The primary objective of the project is to characterise and measure the auditory perception of subjects with misophonia compared with the auditory perception of control subjects.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: For all participants * Obtain oral consent from the participant after receiving information about the study, * Be 18 years or older on the day of inclusion, * Be fluent in French (spoken and written), * Have no known hearing loss, verified by pure tone audiometry. * Declare that they do not have tinnitus, * Declare that they do not have hyperacusis, verified by measuring discomfort thresholds. * Be affiliated to the social security or equivalent scheme. For participants with misophonia: \- Declare discomfort, reduced tolerance to specific sounds (mouth noises, throat clearing, breathing, etc.). Exclusion Criteria: * Bear the after-effects of an ear infection and/or have a history of an ENT disease that permanently affects hearing or balance (vestibular schwannoma, Ménière's disease, sudden or fluctuating deafness, congenital hypoacusis), * Be under guardianship, * deprived of liberty by judicial or administrative decision, or subject to legal protection.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

score on a visual analogue scale from 0 (pleasant sound) to 10 (unpleasant sound)

Timeframe: 1 week after enrollment

score on a visual analogue scale from 0 (very low intensity) to 10 (extremely intense)

Timeframe: 1 week after enrollment

Trial details

NCT IDNCT06921187

SponsorInstitut Pasteur

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2026-03

Contact for this trial

Arnaud Norena

+33488576863 arnaud.norena@univ-amu.fr

View on ClinicalTrials.gov More Misophonia trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.