Ultrasonographic Evaluation of the Effects of Different Wrist Positions on the Median Nerve in Patients With Generalized Joint Hypermobility

Inclusion Criteria: * 15-45 years of age * Female gender * Diagnosed with GJH according to the hypermobility spectrum disorders definition * Patients who agree to participate in the study and provide written consent Exclusion Criteria: * Having wrist pain * Inability to complete full range of motion in the wrist joint * Patients diagnosed with carpal tunnel syndrome * Anatomical abnormalities (bifid median nerve, aberrant persistent median artery, Martin-Gruber or other anastomoses) * History of trauma, operation, fracture, or steroid injection of the hand/wrist * History of known rheumatological, hereditary, genetic disease, or connective tissue disease other than GJH * Having neurological disease affecting hand functions (cervical radiculopathy, peripheral nerve lesion, polyneuropathy, cerebrovascular event, etc.) * Patients with history of regular steroid or non-steroid use, receiving oral glucosamine/hyaluronate supplementation * Those with systemic diseases (inflammatory joint diseases, diabetes mellitus, acromegaly, hypothyroidism, kidney failure, etc.) * Having a body mass index (BMI) of 30 or above, or history of morbid obesity * Being pregnant or in lactation period * Presence of malignancy