"How Blood Flow Restriction Exercise Affects Muscle Oxygenation and Lactate in Elite Athletes" (NCT06918314) | Clinical Trial Compass
CompletedNot Applicable
"How Blood Flow Restriction Exercise Affects Muscle Oxygenation and Lactate in Elite Athletes"
Turkey (Türkiye)46 participantsStarted 2024-07-01
Plain-language summary
This study investigates the effects of blood flow restriction (BFR) training combined with low-intensity aerobic exercise on muscle oxygenation, total hemoglobin (THb), and blood lactate levels in elite athletes, comparing them with healthy sedentary individuals. BFR training, which partially restricts arterial and fully restricts venous blood flow using a pneumatic cuff, creates a hypoxic environment, leading to muscle strength and endurance improvements with lower-intensity exercise. The study aims to determine whether BFR-induced occlusion enhances muscle adaptation and how these physiological responses differ between elite athletes and sedentary individuals.
Who can participate
Age range
15 Years – 18 Years
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Eligibility Criteria:
Participants will be included or excluded based on the following conditions:
Inclusion Criteria:
Willingness to participate in the study
Male individuals aged 15-18 years
Sedentary status for control group participants (\<600 MET-min/week according to the International Physical Activity Questionnaire - Short Form)
Body mass index (BMI) \<25 kg/m²
Licensed track and field athlete for the study group
At least 3 years of experience as a licensed sprint athlete
No history of sports injury in the last 6 months
Exclusion Criteria:
Presence of open wounds or infection in the lower extremities
Leg pain, varicose veins, or thrombophlebitis
Diabetes or a history of cardiovascular disease
Smoking and/or alcohol consumption
Presence of respiratory distress
Bilateral lower extremity pain and edema
Incompatibility with the blood flow restriction (BFR) device
Presence of diseases causing endothelial dysfunction (e.g., hypertension, cardiovascular diseases, neurological disorders, systemic inflammation, obesity, diabetes, atherosclerosis)
History of deep vein thrombosis (DVT) or peripheral vascular disease
Presence of acute infection
History of cancer
Surgical operation due to trauma within the last 6 months
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in muscle oxygenation (SmO₂) measured by Moxy Muscle Oxygen Monitor (Near-Infrared Spectroscopy - NIRS)
Timeframe: Over a period of 2 months
2
Change in blood lactate concentration measured by portable lactate analyzer (e.g., Lactate Scout+)
Timeframe: Immediately before and 3 minutes after each exercise session over a 2-month period
3
Change in body fat percentage measured by Bioelectrical Impedance Analysis (TANITA BIA device)
Timeframe: Over a period of 2 months
4
Change in muscle mass measured by Bioelectrical Impedance Analysis (TANITA BIA device)
Timeframe: Baseline and end of 2-month intervention
5
Change in Body Mass Index (BMI) measured by Bioelectrical Impedance Analysis (TANITA BIA device)
Timeframe: Baseline and end of 2-month intervention