Active — Not RecruitingPhase 1

Fentanyl Versus Midazolam as an Adjunct to Spinal Anesthesia

Lebanon80 participantsStarted 2025-04-01

Plain-language summary

It is well documented in the practice of anesthesia the effectiveness of bupivacaine when added with other adjuvants including midazolam, opioids, and ketamine during neuraxial spinal block for cesarean delivery, however comparison of the superiority of midazolam 2mg over fentanyl 25 micrograms or vice versa with bupivacaine during cesarean delivery has not been established and if performed diligently, could potentially change our understanding and current practice for better patient outcomes.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients aged 18-45 with American Society of Anesthesia (ASA) class II will be included in the study. Exclusion Criteria: * patients with history of opioid substance abuse * pre-eclampsia or eclampsia * Gestational Hypertension * uncontrolled diabetes mellitus * significant cardiac, renal, and hepatic morbidity (i.e., ASA class III patients).

What they're measuring

rescue analgesia

Timeframe: 24 Hours

Trial details

NCT IDNCT06917898

SponsorMakassed General Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-04-30

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