Confirmatory Study on the Efficacy and Safety of the Fixed-dose Combination of Desloratadine/Betamethasone Versus Desloratadine

Inclusion Criteria: * Willing to participate in the study and able to provide written informed consent. * Clinical diagnosis (based on medical history and physical examination) of active allergic rhinitis at study entry. * Patients presenting with moderate to severe nasal symptoms, with a Total Nasal Symptom Score (TNSS) ≥5. * In the case of women of childbearing potential who are sexually active, the use of an acceptable contraceptive method (barrier and/or hormonal), as determined by the investigator. * In the opinion of the Principal Investigator or treating physician, the patient is indicated for treatment with the investigational product and may derive clinical benefit from it. Exclusion Criteria: * Patients for whom the investigational drug is medically contraindicated. * Known allergy or hypersensitivity to the active ingredient, study medications, related products, or excipients. * History of nasal trauma (surgical or accidental) within the past week. * Positive pregnancy test, pregnant or breastfeeding women, or women planning to become pregnant during the course of the study. * Acute or chronic lower or upper respiratory tract infections, such as the common cold, influenza, pneumonia, bronchitis, or chronic sinusitis. * History of non-allergic rhinitis, such as chronic non-allergic rhinitis, drug-induced rhinitis, atrophic rhinitis, hormonal rhinitis, or unilateral rhinitis, as reported in the medical history or patient interview. * History of nasal polyposis, pr…