RCT Comparing Upper Body vs. Combined Exercise Protocols During Active Diabetic Foot Ulcer Treatment

Inclusion Criteria: Age: Adults aged 18 years or older. Diagnosis: Confirmed diagnosis of Type 1 or Type 2 diabetes. Active DFU: Presence of a diabetic foot ulcer under active treatment, as documented by the wound care team. Wound Stability: Ulcer size that meets protocol criteria (e.g., \<2 cm² or ≥2 cm²) and without critical limb ischemia. Ability to Exercise: Medical clearance from a physician to safely participate in unsupervised upper body and non-weight bearing exercises. Compliance: Capacity and willingness to adhere to the study protocol, including scheduled exercise sessions and offloading procedures. Glycemic Control: Stable glycemic control medications regimen for at least 4 weeks prior to enrollment. Informed Consent: Ability to provide written informed consent. Exclusion Criteria: Critical DFU Complications: Ulcers with signs of critical limb ischemia, severe infection (e.g., osteomyelitis), or wound deterioration that contraindicates participation. Cardiovascular Limitations: Unstable cardiac conditions (e.g., uncontrolled arrhythmias, recent myocardial infarction within 6 months), severe heart failure, or any other condition contraindicating exercise. Neurological or Musculoskeletal Limitations: Conditions that significantly impair upper body or core exercise performance (e.g., severe arthritis, recent upper body injury). Cognitive Impairment: Significant cognitive or psychiatric disorders that would limit the ability to provide informed consent or a…