Direct-to-angio Approach From loCal hOspitals Based on a PoInt-of-care bLOod Test for LVO

Inclusion Criteria: * Age: 21 to 85 years old * Language: Speak and understand Spanish or English * Residence: Resident of Puerto Rico * Clinical presentation: Suspected acute stroke * Time of presentation: Monday to Friday, between 8:00 a.m. and 4:00 p.m. * Time of symptom onset: symptoms are known to have begun within the last 6 hours, OR last known to be well between 6 and 18 hours ago, confirmed by a reliable witness or healthcare professional Exclusion Criteria: * Previous healthcare encounter: * Already assessed at another hospital, and ambulance admission is a transfer for continuing care OR * Received thrombolysis therapy before consent (e.g., tPA, alteplase) * Medical History: diagnosed with any of the following in the past 4 weeks: deep vein thrombosis (DVT), pulmonary embolism (PE), arterial embolism, stroke, transient ischemic attack (TIA), long bone fracture, major trauma, surgery under general anesthesia, or head injury requiring hospital admission within the last 4 weeks. * Modified Rankin Scale: Pre-stroke mRS ≥ 3 * The patient is a pregnant woman * The patient is under legal custody or deprived of liberty in penitentiary institutions * The patient is unable to provide informed consent on their own and whose authorized legal representatives are unavailable in person or by telephone during recruitment