Effect of Intraarticular Ozone, Prolotherapy or Dexmedetomidine in Pain Limitation in Knee Osteoarthritis

Inclusion Criteria: * Age from 30 to 65 years. * Both genders. * Patients diagnosed with stage 1-3 osteoarthritis according to the Kellgren-Lawrence Classification System (K-L). Exclusion Criteria: * Patient refusal. * History of knee trauma within the past month. * Rheumatic disease. * Pregnancy. * Any surgical intervention of the knee. * Severe cardiovascular disease. * Morbid obese patients (body mass index (BMI) of \>35 kg/m2). * Local infection at the site of injection. * Bleeding diathesis.